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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX16
All Species:
26.67
Human Site:
S194
Identified Species:
45.13
UniProt:
O14662
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14662
NP_001001433.1
325
37031
S194
M
K
N
R
E
E
R
S
Q
H
F
F
D
T
S
Chimpanzee
Pan troglodytes
XP_514749
272
31071
T159
M
D
D
G
D
D
N
T
L
Y
H
R
G
F
T
Rhesus Macaque
Macaca mulatta
XP_001084615
321
36481
Q191
K
N
R
E
E
R
S
Q
H
F
F
D
T
S
V
Dog
Lupus familis
XP_853504
326
37253
S195
M
K
N
R
E
E
R
S
Q
H
F
F
D
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVI5
326
37034
S195
M
K
N
R
E
E
R
S
Q
H
F
F
D
T
P
Rat
Rattus norvegicus
O70257
261
29832
T149
F
V
S
W
E
S
Q
T
Q
P
Q
V
Q
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511120
304
34831
T191
M
D
D
G
E
D
N
T
L
Y
D
R
G
F
T
Chicken
Gallus gallus
NP_001006295
326
37263
S195
M
K
S
R
E
E
R
S
K
H
F
F
D
T
S
Frog
Xenopus laevis
NP_001085029
304
35171
T191
I
D
D
G
E
D
N
T
L
Y
D
R
G
F
T
Zebra Danio
Brachydanio rerio
XP_691316
324
37513
S194
M
K
N
R
E
E
R
S
K
H
F
F
D
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
V179
L
E
E
G
N
S
S
V
F
T
Q
G
I
I
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O16000
291
33234
T179
S
G
N
P
G
V
F
T
Q
G
I
I
T
D
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SWH4
323
36414
V191
Q
K
E
G
Q
D
E
V
D
L
E
F
N
V
N
Baker's Yeast
Sacchar. cerevisiae
Q08144
397
45857
P194
L
N
K
D
D
L
K
P
I
R
N
K
A
S
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.3
97.2
95
N.A.
92.9
27.6
N.A.
82.4
88
78.1
78.7
N.A.
21.5
N.A.
21.5
N.A.
Protein Similarity:
100
83.6
98.1
96.9
N.A.
95.7
46.4
N.A.
88
95.4
88
90.4
N.A.
43
N.A.
41.8
N.A.
P-Site Identity:
100
6.6
13.3
100
N.A.
93.3
13.3
N.A.
13.3
86.6
6.6
80
N.A.
0
N.A.
13.3
N.A.
P-Site Similarity:
100
46.6
20
100
N.A.
93.3
33.3
N.A.
46.6
100
46.6
93.3
N.A.
13.3
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.6
22.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.9
43.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
22
22
8
15
29
0
0
8
0
15
8
36
8
0
% D
% Glu:
0
8
15
8
65
36
8
0
0
0
8
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
8
0
8
8
43
43
0
22
0
% F
% Gly:
0
8
0
36
8
0
0
0
0
8
0
8
22
0
8
% G
% His:
0
0
0
0
0
0
0
0
8
36
8
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
8
0
8
8
8
8
0
% I
% Lys:
8
43
8
0
0
0
8
0
15
0
0
8
0
0
0
% K
% Leu:
15
0
0
0
0
8
0
0
22
8
0
0
0
0
0
% L
% Met:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
15
36
0
8
0
22
0
0
0
8
0
8
0
8
% N
% Pro:
0
0
0
8
0
0
0
8
0
8
0
0
0
0
8
% P
% Gln:
8
0
0
0
8
0
8
8
36
0
15
0
8
0
8
% Q
% Arg:
0
0
8
36
0
8
36
0
0
8
0
22
0
0
0
% R
% Ser:
8
0
15
0
0
15
15
36
0
0
0
0
0
22
22
% S
% Thr:
0
0
0
0
0
0
0
36
0
8
0
0
15
29
29
% T
% Val:
0
8
0
0
0
8
0
15
0
0
0
8
0
15
8
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
22
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _